The Pacific Regional Science Conference Organisation (PRSCO) was established at the 7th Annual Meeting of the Western Regional Science Association (WRSA) in San Diego, February 1-4, 1968 at the initiative of representatives from WRSA and the Japan Section of the Regional Science Association (JSRSA). The first conference of PRSCO was held at the East-West Center, University of Hawaii, August 26-29, 1969. Subsequently, full conferences and smaller meetings have been held in many countries in the Pacific Rim area. A full international conference is held every second year and a smaller summer institute in alternate years.

The PRSCO is one of the 4 supra-regional associations of RSAI (Regional Science Association International) which is founded in 1954. The PRSCO enhances and facilitates exchange of research information in the field of regional science among members of Membership Sections of the PRSCO, as well as the exchange of this information in the Pacific Rim area between such members and other persons with an interest in regional science.

The PRSCO is a federation of the following affiliated sections/associations of the Regional Science Association International in the Pacific Rim Area.